Dr. Antonio da Silva of Dadar, in 1868, through the good offices of Rev. Father John Braz Fernandes left by his will the bulk of his estate for the founding of a high school for the education of the indigenous Catholic boys of the place. Non-Catholic boys, however, are also admitted. This school came to be known as Dr. Antonio da Silva High School.

This School started a Technical Stream from Std. VIII in June 1963. It became a full-fledged independent Technical High School on 13th June 1971, and is at present located in its new premises at S. Veer Savarkar Marg, (Cadell Road), Dadar.

The First Year Junior College classes, Science with Biology stream and Science with Technical stream, were started in July 1975. Two Vocational Courses viz., Electrical Maintenance and Scooter and Motor Cycle Servicing were started at the Junior College level in September 1978 and Mechanical Maintenance course from June 1986 (in place of Science with Technical course). This Institution is thus a full-fledged Junior College with Science and Vocational Streams and is now called Dr. Antonio da Silva Technical High School and Junior College of Science.

From June 2021, the School and College have now become a Co-Ed Institute. Students are admitted to this Institution in the eighth and eleventh (F.Y.J.C.) standards. Admissions to Std. VIII commence during the first week of May, as soon as Std. VII results are declared. Admissions to F.Y.J.C. Classes commence soon after the declaration of S.S.C. Examination results. Students should submit the application for admission to F.Y.J.C. class within three days of the declaration of S.S.C. results.

The medium of instruction is English. The institution is recognised and aided by the Directorate of Vocational Education and Training, Maharashtra State and prepares pupils for the Secondary School Certificate Examination (with technical subjects) and Higher Secondary Certificate Examination (with pure science / vocational science subjects) of the S. Veer Savarkar Marg (Cadell Road) Dr. Antonio da Silva Technical High School and Junior College of Science 7 Pupils coming from recognized schools within the State, must produce a leaving certificate from the last school attended. Those coming from schools outside the State must produce a leaving certificate countersigned by the Education Officer of that state.

Pupils coming from other boards or Council must produce complete set of documents. It is the responsibility of the students and parents to submit all necessary documents well in advance, for verification and for eligibility Certificate from MSBSHSE.

Pupils coming from unrecognized schools will be subjected to a written test in all the subjects. The parent or guardian must produce an affidavit made before a Stipendiary Magistrate clearly stating (1) the reason why the pupil did not join any recognised school, (2) the name of the unrecognized school attended, (3) the standard attended and the subjects studied by him, (4) the examination passed if any, (5) the date of birth. (Such admissions are made provisionally subject to confirmation by the Education Inspector).